Introducing Soleus Health

You've heard about your second heart.
We built the device for it.

2HEART is a closed-loop circulatory monitoring device that activates the soleus muscle during seated use and measures plantar vascular response in real time.

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The problem

Sitting has quietly become one of the biggest challenges in modern health.

When you sit for hours, your soleus muscle goes silent. And when that muscle stops working, so does the natural pump that moves blood from your legs back to your heart.

77M+

People living with diabetes in India

8–12

Hours the average professional sits each day

90mmHg

Venous pressure in feet when standing perfectly still

60%

Of total blood volume carried in the venous system

"The second heart is in your calves. Every step, every heel raise, every muscle squeeze pushes blood back to your real heart, keeps your circulation alive, and stops deadly clots from forming. When your second heart fails, your first one is forced to work harder."

— Dr. Dmitry Yaranov, Advanced Heart Failure & Transplant Cardiologist

Meet the soleus

A muscle built for stillness — and circulation.

Deep in your calf sits a muscle unlike any other. The soleus is designed for endurance, not intensity. It doesn't tire easily, doesn't need glycogen, and when activated correctly, it becomes one of the most metabolically active tissues in your body.

Runs on a different fuel

Unlike other muscles, the soleus draws energy directly from blood glucose and circulating fats — not stored glycogen. This makes it uniquely suited to sustained, low-intensity activity.

Your body's venous pump

The soleal pump assists venous return from the periphery to the heart. The venous circulatory system literally passes through the muscle tissue — making it a circulatory engine, not just a postural muscle.

Silent when you sit

When seated with knees at 90°, the gastrocnemius is virtually inactive and load is borne almost entirely by the soleus. For most people sitting 8+ hours a day, this pump never activates.

The science

Research-backed. Not a wellness trend.

The science of the soleus and its role in circulatory health has been building for years. These are the findings that matter — attributed to the researchers who made them, not to us.

52%

reduction

Post-meal glucose response

Soleus push-up contractions sustained during a glucose tolerance test reduced post-meal glucose excursion by approximately 52% compared to continuous sitting.

Hamilton et al., iScience, University of Houston, 2022

32%

improvement

Glucose regulation in prediabetics

A 2025 pilot study found that performing the soleus push-up while seated resulted in a 32% reduction in postprandial glucose excursion in prediabetic individuals — without EMG feedback or lab equipment.

Elek et al., Sports (MDPI), 2025 — PubMed PMID: 40137805

26%

reduction

Insulin response with 3-minute intervals

Interrupting prolonged sitting every 30 minutes with just 3 minutes of soleus activation may reduce the insulin response by up to 26%, supporting more efficient metabolic regulation throughout the day.

As reported by Verywell Health, 2025

2×

higher risk

Calf pump function and VTE risk

A population-based Mayo Clinic cohort study of 1,532 patients found that reduced calf muscle pump function was associated with doubled risk of venous thromboembolism and was an independent predictor of all-cause mortality.

Houghton et al., Blood Journal, Mayo Clinic, 2021

48%

less likely

Leg strength and heart failure

Patients with high leg muscle strength were 48% less likely to develop heart failure after a heart attack compared to those with low leg muscle strength, in a study of approximately 1,000 patients over four years.

European Journal of Preventive Cardiology, May 2024 — via Harvard Health

Hours

without fatigue

Unique endurance of the soleus

The soleus can raise local oxidative metabolism to high levels for hours without fatigue during seated activity — even in unfit volunteers. It runs on blood glucose, not glycogen, making it uniquely suited for sustained low-intensity use.

Hamilton et al., iScience, 2022 — the founding study

Research institutions

University of Houston Mayo Clinic Harvard Health Publishing Cleveland Clinic European Journal of Preventive Cardiology PubMed / NIH

How 2HEART works

Active. Not passive. Closed-loop.

Unlike passive monitoring devices that simply observe, 2HEART activates the soleus and immediately measures what happens next — creating a closed loop between muscle activation and vascular response.

Soleus activation

2HEART prompts and facilitates activation of the soleus muscle during seated use — the precise muscle Dr. Hamilton identified as requiring wearable technology to optimise its benefits.

Plantar vascular measurement

Immediately after activation, 2HEART measures the plantar vascular response — how quickly and how much blood returns to the foot. This response is a real-time signal of circulatory activity.

Closed-loop feedback

The loop closes: activation triggers a response, the response is measured, and the data reflects what's happening in your circulatory system at that moment — in real time, while you sit.

Real-time insight

You see what's happening in your body's circulatory patterns — not a step count, not a heart rate average, but a direct measurement of your body's second heart in action.

⚡

Active measurement

Engages the soleus, then measures response — not just passive observation

🔄

Closed-loop design

Activation and vascular response measured in the same session

📍

Plantar vascular focus

Measures at the foot — where 95% of vascular resistance signals originate

🪑

Designed for seated use

Works during the workday — no disruption, no gym required

⏱

Real-time data

Vascular response measured immediately after activation — not averaged over days

🏥

Clinical & wellness ready

Designed for hospitals, wellness clinics, and corporate health programs

Who it's for

Soleus health affects everyone who sits.

2HEART is built for anyone whose circulatory health is affected by prolonged sitting — which, in the modern world, is most of us.

The sedentary professional

Desk-bound for 8+ hours a day. Feels the afternoon energy drop. Wants to understand what's happening in their body during those long sitting hours — without leaving their chair.

Office worker Corporate wellness Remote work

The health-aware individual

Already tracks steps, sleep, and heart rate. Ready to add the next layer — real-time circulatory awareness. Wants to know if the 3-minute soleus routine is actually doing anything for their specific body.

Biometric tracking Preventive health Wellness tech

Hospitals & clinics

Looking for a non-invasive, real-time tool to assess lower limb circulatory patterns in patients — particularly those with sedentary risk profiles or circulatory concerns.

Clinical assessment Vascular health Patient monitoring

Corporate wellness programs

Responsible for the health of hundreds of desk-bound employees. Needs a scalable, evidence-informed tool that fits into the workday — not a gym programme nobody uses.

Employee health HR & benefits Scalable wellness

The conversation is building

The world is waking up to the soleus.

From peer-reviewed research to India's biggest newspapers — the second heart is becoming mainstream. 2HEART arrives at exactly the right moment.

2022 — University of Houston

The founding discovery

Dr. Marc Hamilton's team publishes in iScience — the soleus push-up reduces post-meal glucose by 52%. Hamilton notes the movement requires wearable technology to optimise its benefits.

2023–2024 — Global media

The second heart goes viral

Dr. Yaranov's "you have two hearts" post spreads globally. Cleveland Clinic, Mayo Clinic, and Harvard Health all publish guidance on calf muscle health. The Glucose Goddess reaches 5.5M followers with soleus push-up demonstrations.

2025 — India wakes up

Mainstream Indian coverage begins

Hindustan Times, Indian Express, Times of India, Economic Times, and ABP Live all cover the second heart and soleus health. Indian endocrinologists and vascular surgeons publicly validate the science. The category arrives in India.

2026 — Right now

2HEART enters development

Girsan Innovations begins building the device Dr. Hamilton said was needed. The first closed-loop soleus health monitoring device. The tool that tells you if your second heart is working.

Hindustan Times Indian Express Times of India Economic Times ABP Live The Tribune iScience / Cell Press Blood Journal / ASH Harvard Health

FAQ

Common questions.

Everything you need to know about Soleus Health and 2HEART.

Soleus Health is a new category we're defining — it refers to the activation and monitoring of the soleus muscle for circulatory awareness. The soleus, often called the "second heart," plays a crucial role in returning blood from the legs to the heart. When it's inactive — as it is during prolonged sitting — circulation in the lower body slows. Soleus Health is about understanding and supporting this function in everyday life.

2HEART measures plantar vascular response — the speed and volume of blood flow returning to the foot after the soleus muscle is activated. This closed-loop measurement reflects real-time circulatory activity in the lower limb. It is a measurement tool, not a diagnostic device.

Fitness trackers measure steps, heart rate, and calories — all passive observations of what your body is already doing. 2HEART is active: it engages the soleus and immediately measures the vascular response. This closed-loop approach gives you a direct signal of circulatory activity that no step counter or wrist-based heart rate monitor can provide.

2HEART is a circulatory monitoring and wellness device. It measures plantar vascular response in real time. It is not intended to diagnose, treat, cure, or prevent any disease or medical condition. For any health concerns, please consult a qualified medical professional.

2HEART is currently in development by Girsan Innovations Private Limited, New Delhi. The first prototype is expected in mid-2026, followed by clinical feasibility studies. Waitlist members will be among the first to know about availability, early access programmes, and launch updates.

2HEART is being developed by Girsan Innovations Private Limited, a medical technology startup based in New Delhi, India. The company is focused on creating the world's first closed-loop soleus health monitoring device — the tool that Dr. Marc Hamilton identified as necessary to optimise the benefits of soleus activation.

You've heard about your second heart.We built the device for it.